Resident Evil Requiem [All Puzzle Solutions]

Chairman’s Office Puzzle Box
Moon – Sun – Star – Moon


Lead Researcher’s Office Puzzle Box
Star – Sun – Moon – Sun


Security Manager’s Office Puzzle Box (Braille)
Read the notebook on the desk → interact with the Puzzle Box to get the Level 3 Wristband → use it on Emily’s cell → bring her back to the Puzzle Box → she solves it automatically.

Analyzer Blood Specimen (Denatured)
Select the square in the left-center position.


Analyzer Blood Specimen (Converged)
Pick the top-middle square → then the second square from the bottom.


Analyzer Blood Specimen (Reversible)
Press bottom-left → center → top-right → square just under the top one.


Analyzer Blood Specimen (Polymerized)
(Insanity only)
Activate middle-left → middle-right → middle-bottom.

Inspect the Organ Transport Box in inventory
→ rotate to reach the back panel
→ set bottom-right switch to HAND
→ move the right switch to the middle
→ press Button 5 down
→ press Button 2 down
→ return bottom-right switch to AUTO.

Bar & Lounge Safe
Left 10 – Right 80 – Left 30
Insanity: Right 20 – Left 50 – Right 30

Examination Room Safe
Right 30 – Left 10 – Right 50
Insanity: Left 50 – Right 30 – Left 90

Basement Safe
Right 60 – Left 40 – Right 80
Insanity: Left 70 – Right 50 – Left 20

Sterilization Chamber Safe
Right 10 – Left 90 – Right 20
Insanity: Left 80 – Right 50 – Left 0

Monitor Control Room Safe
Left 50 – Right 60 – Left 80
Insanity: Right 20 – Left 0 – Right 70

Inspect the wine bottle → rotate it to reveal the hidden Double Helix Model → insert it into the lectern.